Crosstalk between cancer-associated fibroblasts and non-neuroendocrine tumor cells in small cell lung cancer involves in glycolysis and antigen-presenting features

Crosstalk between cancer-associated fibroblasts and non-neuroendocrine tumor cells in small cell lung cancer involves in glycolysis and antigen-presenting features

Abstract Background Small cell lung cancer (SCLC) is a highly fatal malignancy, the complex tumor microenvironment (TME) is a critical factor affecting SCLC progression. Cancer-associated fibroblasts (CAFs) are crucial components of TME, yet their role in SCLC and the underlying mechanisms during th...

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Bibliographic Details
Main Authors: Yuanhua Lu, Hui Li, Peiyan Zhao, Xinyue Wang, Wenjun Shao, Yan Liu, Lin Tian, Rui Zhong, Haifeng Liu, Ying Cheng
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Molecular Medicine
Subjects:
SCLC
CAF
Glycolysis
STING signaling
Antigen presentation
Online Access:https://doi.org/10.1186/s10020-024-01051-y
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