Identification of CTSK as a TLR-related critical biomarker in liver cirrhosis via integrative bioinformatics and pathological characterization

Identification of CTSK as a TLR-related critical biomarker in liver cirrhosis via integrative bioinformatics and pathological characterization

Abstract Liver cirrhosis (LC) is a common chronic disease worldwide with a poor prognosis, and its pathogenesis has not been fully elucidated. Toll-like receptors (TLRs) are crucial in LC progression. Here, we identified TLR-related genes, providing novel insights related to LC diagnosis, pathogenes...

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Main Authors: Jiaxin Wang, Ning Li, Xueyu Cang, Xuerong Liu, Ranyan Gao, Lingyi Xu, Fengchun Li, Xinyu Jiang, Hongliang Chen, Xinyu Geng, Jihan Qi, Ram Prasad Chaulagain, Junchong He, Shizhu Jin
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Liver cirrhosis
Toll-like receptors
Biomarkers
CTSK
Online Access:https://doi.org/10.1038/s41598-025-11606-6
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https://doi.org/10.1038/s41598-025-11606-6

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