Appraisal of multiple polygenic risk scores to estimate the risk of myocardial infarction and coronary artery lesions

Appraisal of multiple polygenic risk scores to estimate the risk of myocardial infarction and coronary artery lesions

Abstract Background Polygenic risk scores (PRS) could help to identify individuals with a high genetic risk profile for coronary artery disease (CAD). We aimed to evaluate the association between previously reported PRS and myocardial infarction (MI) as well as the extent and recurrence of coronary...

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Main Authors: Hasanga D. Manikpurage, Jérôme Bourgault, Ursula Houessou, Audrey Paulin, Pardis Zamani, Eloi Gagnon, Zhonglin Li, Dominique K. Boudreau, Aida Eslami, Pierre Voisine, Patrick Mathieu, Yohan Bossé, Benoit J. Arsenault, Sébastien Thériault
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00981-w
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https://doi.org/10.1038/s43856-025-00981-w

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