Short-term high-fat diet post-ACLT surgery activates chondrocyte AMPK pathway and slows articular cartilage degeneration in rats

Short-term high-fat diet post-ACLT surgery activates chondrocyte AMPK pathway and slows articular cartilage degeneration in rats

Osteoarthritis is often exacerbated by obesity and metabolic syndrome, which are frequently associated with high-fat diets (HFD). This study investigates the direct effects of HFD on articular cartilage following anterior cruciate ligament transection (ACLT) in rats, while also examining the role of...

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Bibliographic Details
Main Authors: Hongri Ruan, Tingting Zhu, Tianwen Ma, Yun Liu, Jiasan Zheng
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Functional Foods
Subjects:
High-fat diet
Post-traumatic osteoarthritis
Cartilage
Extracellular matrix
AMPK
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624006121
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