Toward Identification of Markers for Brain‐Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large‐Scale, Unbiased Analysis Using Proximity Extension Assays

Toward Identification of Markers for Brain‐Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large‐Scale, Unbiased Analysis Using Proximity Extension Assays

ABSTRACT Extracellular vesicles (EVs) captured in biofluids have opened a new frontier for liquid biopsies. To enrich for vesicles coming from a particular cell type or tumour, scientists utilize antibodies to transmembrane proteins that are relatively unique to the cell type of interest. However, r...

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Bibliographic Details
Main Authors: Maia Norman, Adnan Shami‐shah, Sydney C. D'Amaddio, Benjamin G. Travis, Dmitry Ter‐Ovanesyan, Tyler J. Dougan, David R. Walt
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Journal of Extracellular Vesicles
Subjects:
brain‐derived extracellular vesicles
membrane association
Olink
proteomics
size exclusion chromatography
Online Access:https://doi.org/10.1002/jev2.70052
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https://doi.org/10.1002/jev2.70052

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