Anti-Obesity Effects of Adzuki Bean Saponins in Improving Lipid Metabolism Through Reducing Oxidative Stress and Alleviating Mitochondrial Abnormality by Activating the PI3K/Akt/GSK3β/β-Catenin Signaling Pathway

Anti-Obesity Effects of Adzuki Bean Saponins in Improving Lipid Metabolism Through Reducing Oxidative Stress and Alleviating Mitochondrial Abnormality by Activating the PI3K/Akt/GSK3β/β-Catenin Signaling Pathway

Obesity is a chronic and complex disease defined by the excessive deposition of fat and is highly associated with oxidative stress. Adzuki bean saponins (ABS) showed anti-obesity activity in our previous in vivo study; however, the active saponins of adzuki beans and potential mechanisms are still u...

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Bibliographic Details
Main Authors: Jinhai Luo, Jincan Luo, Yingzi Wu, Yu Fu, Zhonghao Fang, Bincheng Han, Bin Du, Zifeng Yang, Baojun Xu
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Antioxidants
Subjects:
adzuki bean
obesity
lipid metabolism
network pharmacology
mitochondrial function
Online Access:https://www.mdpi.com/2076-3921/13/11/1380
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