Enhancing the confidence of potential targets enriched by similarity-centric models: the crucial role of the similarity threshold
BackgroundComputational target fishing (TF) tools have made tremendous progress in narrowing down the set of potential targets, thereby expediting time- and resource-consuming wet-lab experiments. Among these tools, similarity-centric TF methods are particularly prominent and extensively employed to...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1574540/full |
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