Exploring the role of tumor to background parenchymal ratio of the [18F]FLT PET/CT measures in determining response to neoadjuvant chemotherapy in breast cancer: a multicenter study

Exploring the role of tumor to background parenchymal ratio of the [18F]FLT PET/CT measures in determining response to neoadjuvant chemotherapy in breast cancer: a multicenter study

Abstract Objective To investigate the potential of 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography computed tomography ([18F]FLT PET/CT) in predicting locally advanced breast cancer response to neoadjuvant chemotherapy (NAC), focusing on the role of tumor to background parenc...

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Bibliographic Details
Main Authors: Alisa Mohebbi, Fatemeh Asli, Saeed Mohammadzadeh, Ali Abbasian Ardakani, Seyed Mohammad Tavangar, Afshin Mohammadi
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
Breast cancer
Computed tomography (CT)
Positron emission tomography/computed tomography (PET/CT)
18F-fluorothymidine ([18F]FLT)
Neoadjuvant chemotherapy (NAC)
Diagnostic test accuracy (DTA)
Online Access:https://doi.org/10.1186/s12885-025-14534-w
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https://doi.org/10.1186/s12885-025-14534-w

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