IGSF9-targeted therapy inhibits the progression of acute myeloid leukemia

IGSF9-targeted therapy inhibits the progression of acute myeloid leukemia

Abstract: Previously, we reported that targeting immunoglobulin superfamily member 9 (IGSF9) could enhance antitumor T-cell activity and sensitivity to anti–PD-1 immunotherapy, although the detailed mechanism remains unclear. In this study, we find that, similar to the regulation of PD-L1 expression...

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Main Authors: Lijun Hui, Jing Xiao, Zhiling Zhao, Juan Zhang, Huiwen Luan, Jiashen Zhang, Yuxiao Sun, Xianhui Meng, Hongying Wang, Chunling Li, Fangmin Li, Shuhao Ji, Shuping Wei, Fang Li, Hong Yu, Chengyun Zheng, Yang Jiang, Yaopeng Wang, Zunling Li
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925003386
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