Analytical strategies for identification and quantitation of heterodimers in co-formulated monoclonal antibody cocktails by native SEC-MS
Abstract Co-formulation of two or more therapeutic monoclonal antibodies (mAbs) into one final drug product has gained significant popularity recently due to its numerous advantages, including enhanced efficacy, reduced overall adverse events, and improved patient convenience and compliance. However...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-13986-1 |
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