Enhancement of SARS-CoV-2 Receptor Binding Domain -CR3022 Human Antibody Binding Affinity via In silico Engineering Approach

Introduction: The angiotensin-converting enzyme 2 (ACE2) is the effective primary receptor for SARS-CoV-2. The interaction between ACE2 and the spike protein of the virus is the crucial step for virus entry into the target cells. ACE2 receptor can be blocked by neutralizing antibodies (nAbs) such...

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Bibliographic Details
Main Authors: Fatemeh Sefid, Zahra Payandeh, Bahman Khalesi, Behzad Mansoori, Marzieh Fotovvat, Maryam Touhidinia
Format: Article
Language:English
Published: Pasteur Institute of Iran 2021-09-01
Series:Journal of Medical Microbiology and Infectious Diseases
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Online Access:https://jommid.pasteur.ac.ir/article-1-345-en.html
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