T cells in cancer: mechanistic insights and therapeutic advances

T cells in cancer: mechanistic insights and therapeutic advances

Abstract T cells are central players in the fight against cancer, capable of recognizing and destroying tumor cells. However, tumors often find ways to evade this immune response, creating challenges for effective treatment. In this review, we explore how different T cell subsets—including cytotoxic...

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Main Authors: Jingjing Pu, Ting Liu, Yi Zhou, Mengping Chen, Xuehang Fu, Yike Wan, Junying Wang, Binzhen Chen, Amit Sharma, Veronika Lukacs-Kornek, Ingo G.H. Schmidt-Wolf, Jian Hou
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Biomarker Research
Subjects:
T cells
Cancer immunotherapy
Tumor microenvironment
Adoptive T cell therapy
Precision treatment
Online Access:https://doi.org/10.1186/s40364-025-00807-w
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https://doi.org/10.1186/s40364-025-00807-w

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