Anxiety and depression in childhood rheumatologic conditions: A topical review

This topical review summarizes recent literature on mental health symptoms experienced by children diagnosed with rheumatologic conditions including childhood-onset systemic lupus erythematosus (cSLE), juvenile idiopathic arthritis (JIA), and juvenile dermatomyositis (JDM). Studies, while limited, g...

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Main Authors: Mallet R Reid, Jacqueline Fabricius, Ashley Danguecan, Kaveh Ardalan, Andrea Knight, Natoshia R Cunningham
Format: Article
Language:English
Published: SAGE Publishing 2021-01-01
Series:Indian Journal of Rheumatology
Subjects:
Online Access:http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2021;volume=16;issue=3;spage=304;epage=310;aulast=Reid
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author Mallet R Reid
Jacqueline Fabricius
Ashley Danguecan
Kaveh Ardalan
Andrea Knight
Natoshia R Cunningham
author_facet Mallet R Reid
Jacqueline Fabricius
Ashley Danguecan
Kaveh Ardalan
Andrea Knight
Natoshia R Cunningham
author_sort Mallet R Reid
collection DOAJ
description This topical review summarizes recent literature on mental health symptoms experienced by children diagnosed with rheumatologic conditions including childhood-onset systemic lupus erythematosus (cSLE), juvenile idiopathic arthritis (JIA), and juvenile dermatomyositis (JDM). Studies, while limited, generally indicate that anxiety and depressive symptoms may be more common among children diagnosed with rheumatologic conditions than non-chronically ill children. Although the rates of clinically significant symptoms are not consistently reported across studies, overall anxiety and depressive symptom rates in cSLE vary between 34%–37% and 6.7%–59%, respectively. A recent systematic review of JIA suggests between 7% and 64% of participants experienced elevated anxiety, and between 7% and 36% of participants reported clinically significant depressive symptoms. Approximately 40% of youth with JDM may experience general psychological distress, but more research is needed. In the available literature, there is mixed support for higher rates of anxiety in JIA as compared to cSLE, and higher rates of depressive symptoms in cSLE as compared to JIA, whereas mental health functioning in JDM is less well understood. Mental health functioning in youth with rheumatologic conditions may be related to increased disease-related impairment. Using consistent mental health screening measures with clinically validated cutoffs would enhance insight into the frequency and impact of anxiety and depressive symptoms experienced. Knowledge would also be enhanced by conducting studies with ethnically representative samples to identify potential disparities in care. An improved understanding of mental health functioning in pediatric patients presenting for rheumatologic care may inform the development and testing of tailored and effective treatments.
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spelling doaj-art-996985d83c4644ba8a3f74a4a5d9a26b2025-01-03T01:45:49ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012021-01-0116330431010.4103/injr.injr_127_20Anxiety and depression in childhood rheumatologic conditions: A topical reviewMallet R ReidJacqueline FabriciusAshley DanguecanKaveh ArdalanAndrea KnightNatoshia R CunninghamThis topical review summarizes recent literature on mental health symptoms experienced by children diagnosed with rheumatologic conditions including childhood-onset systemic lupus erythematosus (cSLE), juvenile idiopathic arthritis (JIA), and juvenile dermatomyositis (JDM). Studies, while limited, generally indicate that anxiety and depressive symptoms may be more common among children diagnosed with rheumatologic conditions than non-chronically ill children. Although the rates of clinically significant symptoms are not consistently reported across studies, overall anxiety and depressive symptom rates in cSLE vary between 34%–37% and 6.7%–59%, respectively. A recent systematic review of JIA suggests between 7% and 64% of participants experienced elevated anxiety, and between 7% and 36% of participants reported clinically significant depressive symptoms. Approximately 40% of youth with JDM may experience general psychological distress, but more research is needed. In the available literature, there is mixed support for higher rates of anxiety in JIA as compared to cSLE, and higher rates of depressive symptoms in cSLE as compared to JIA, whereas mental health functioning in JDM is less well understood. Mental health functioning in youth with rheumatologic conditions may be related to increased disease-related impairment. Using consistent mental health screening measures with clinically validated cutoffs would enhance insight into the frequency and impact of anxiety and depressive symptoms experienced. Knowledge would also be enhanced by conducting studies with ethnically representative samples to identify potential disparities in care. An improved understanding of mental health functioning in pediatric patients presenting for rheumatologic care may inform the development and testing of tailored and effective treatments.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2021;volume=16;issue=3;spage=304;epage=310;aulast=Reidanxietychildhood-onset systemic lupus erythematosusdepressionjuvenile dermatomyositisjuvenile idiopathic arthritismental health
spellingShingle Mallet R Reid
Jacqueline Fabricius
Ashley Danguecan
Kaveh Ardalan
Andrea Knight
Natoshia R Cunningham
Anxiety and depression in childhood rheumatologic conditions: A topical review
Indian Journal of Rheumatology
anxiety
childhood-onset systemic lupus erythematosus
depression
juvenile dermatomyositis
juvenile idiopathic arthritis
mental health
title Anxiety and depression in childhood rheumatologic conditions: A topical review
title_full Anxiety and depression in childhood rheumatologic conditions: A topical review
title_fullStr Anxiety and depression in childhood rheumatologic conditions: A topical review
title_full_unstemmed Anxiety and depression in childhood rheumatologic conditions: A topical review
title_short Anxiety and depression in childhood rheumatologic conditions: A topical review
title_sort anxiety and depression in childhood rheumatologic conditions a topical review
topic anxiety
childhood-onset systemic lupus erythematosus
depression
juvenile dermatomyositis
juvenile idiopathic arthritis
mental health
url http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2021;volume=16;issue=3;spage=304;epage=310;aulast=Reid
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AT kavehardalan anxietyanddepressioninchildhoodrheumatologicconditionsatopicalreview
AT andreaknight anxietyanddepressioninchildhoodrheumatologicconditionsatopicalreview
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