A positive feedback loop between FOSB and miR-133b controls colon cancer cell proliferation

A positive feedback loop between FOSB and miR-133b controls colon cancer cell proliferation

FOSB, a member of the FOS gene family, forms heterodimers with JUN family proteins to engage in diverse cellular processes. Its biological impacts vary among different types of tumors, yet its specific function in colon cancer (CC) remains ambiguous. In this study, quantitative real-time PCR (qRT-PC...

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Bibliographic Details
Main Authors: Li Wanwan, Hu Qionggui, Lin Changwei, Li Xiaorong, Bai Yang, Ma Min
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2025-03-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
colon cancer
FOSB
miR-133b
POU2F1
proliferation
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2025041
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https://www.sciengine.com/doi/10.3724/abbs.2025041

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