Brain organoid methodologies to explore mechanisms of disease in progressive multiple sclerosis

Multiple sclerosis (MS), a debilitating autoimmune disorder targeting the central nervous system (CNS), is marked by relentless demyelination and inflammation. Clinically, it presents in three distinct forms: relapsing–remitting MS (RRMS), primary progressive MS (PPMS), and secondary progressive MS...

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Bibliographic Details
Main Authors: Madalena B. C. Simões-Abade, Marlene Patterer, Alexandra M. Nicaise, Stefano Pluchino
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Cellular Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2024.1488691/full
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