A fibrin gel-loaded Gouqi-derived nanovesicle (GqDNV) repairs the heart after myocardial infarction by inhibiting p38 MAPK/NF-κB p65 pathway

A fibrin gel-loaded Gouqi-derived nanovesicle (GqDNV) repairs the heart after myocardial infarction by inhibiting p38 MAPK/NF-κB p65 pathway

Abstract The restoration of cardiac function post-myocardial infarction (MI) remains a significant clinical challenge. Emerging evidence indicates that Goji berries (“Gouqi” in Chinese) and their extracts exhibit substantial cardioprotective properties. Here, we introduce fibrin gel-loaded Gouqi-der...

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Main Authors: Huan-Huan Zhou, Xiaolei Zhou, Jianqiu Pei, Shiyin Xu, Biyu Jin, Jiuling Chen, Zixuan Zhang, Mingmeng Tang, Yan Liu, Andreas K. Nüssler, Liegang Liu, Qin Xu, Anxin Wang, Min Xia, Wei Yang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Nanobiotechnology
Subjects:
Myocardial infarction
Cardiac patch
Goji berry
Exosome
Plant-derived nanovesicle
Online Access:https://doi.org/10.1186/s12951-025-03615-4
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https://doi.org/10.1186/s12951-025-03615-4

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