Deciphering cancer therapy resistance via patient-level single-cell transcriptomics with CellResDB

Abstract Cancer therapy resistance remains a major challenge, with limited resources available for systematically studying its underlying mechanisms at the patient level. The existing databases are either restricted to bulk RNA-seq data, lack single-cell resolution, or provide limited clinical annot...

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Bibliographic Details
Main Authors: Tianyuan Liu, Huiyuan Qiao, Liping Ren, Xiucai Ye, Quan Zou, Yang Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08457-2
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