Nanocomposite-based PCR reactors to enhance thermal rate and fluorescence intensity in hand-held qPCR device

Nanocomposite-based PCR reactors to enhance thermal rate and fluorescence intensity in hand-held qPCR device

Abstract A photonic quantitative polymerase chain reaction (qPCR) has usually implemented a polydimethylsiloxane (PDMS) based disposable inexpensive PCR reactor, worked as the photothermal cycler, to show potential as a point-of-care test (PoCT) for detection nucleic acids. However, the PoCT type ph...

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Bibliographic Details
Main Authors: Jiyeon Han, Tiara A M, Seongryeong Kim, Gabriela Morales Florez, Kiran Shrestha, Dang Du Nguyen, Inki Kim, Jinkee Lee, Gyoujin Cho
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Nanobiotechnology
Subjects:
Photonic PCR
Plasmonic fluorescence
TiO2-PDMS
Photothermal cycler
Nucleic acid assay
Online Access:https://doi.org/10.1186/s12951-025-03287-0
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https://doi.org/10.1186/s12951-025-03287-0

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