Spall: accurate and robust unveiling cellular landscapes from spatially resolved transcriptomics data using a decomposition network

Abstract Recent developments in spatially resolved transcriptomics (SRT) enable the characterization of spatial structures for different tissues. Many decomposition methods have been proposed to depict the cellular distribution within tissues. However, existing computational methods struggle to bala...

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Bibliographic Details
Main Authors: Zhongning Jiang, Wei Huang, Raymond H. W. Lam, Wei Zhang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-024-06003-1
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