Identification of B Cell Subpopulations with Pro- and Anti-Tumorigenic Properties in an Immunocompetent Mouse Model of Head and Neck Squamous Cell Carcinoma

Identification of B Cell Subpopulations with Pro- and Anti-Tumorigenic Properties in an Immunocompetent Mouse Model of Head and Neck Squamous Cell Carcinoma

Due to their high developmental diversity and different regulatory and functional roles, B cell subpopulations can promote or inhibit tumor growth. An orthotopic murine HNSCC model was applied to investigate the B cell composition and function in HNSCCs. Using flow cytometry approaches, cells from t...

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Bibliographic Details
Main Authors: Michael Sonntag, Sandra Stanojevic, Simon Laban, Patrick J. Schuler, Thomas K. Hoffmann, Cornelia Brunner
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cells
Subjects:
B cells
HNSCC
germinal centers
adenosine
immunocompetent mouse model
Online Access:https://www.mdpi.com/2073-4409/14/1/20
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