Targeting the kynurenine pathway: a novel approach in tumour therapy

Abstract Background Cancer cells interact with their surroundings to promote tumour formation and metastasis, often requiring a constant supply of amino acids. The reprogramming of tryptophan (Trp) metabolism is highly activated in tumours, providing essential biological raw materials and energy f...

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Bibliographic Details
Main Authors: Shuoqi Lin, Genggeng Zheng, Yuxiang Yan, Tesen Liao, Bohua Su, Dali Zheng
Format: Article
Language:English
Published: Cambridge University Press 2025-01-01
Series:Expert Reviews in Molecular Medicine
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Online Access:https://www.cambridge.org/core/product/identifier/S1462399425000055/type/journal_article
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