A data‐driven, multi‐domain brain gray matter signature as a powerful biomarker associated with several clinical outcomes

A data‐driven, multi‐domain brain gray matter signature as a powerful biomarker associated with several clinical outcomes

Abstract INTRODUCTION Characterizing pathological changes in the brain that underlie cognitive impairment, including Alzheimer's disease and related disorders, is central to clinical concerns of prevention, diagnosis, and treatment. METHODS We describe the properties of a brain gray matter regi...

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Bibliographic Details
Main Authors: Evan Fletcher, Brandon Gavett, Sarah Tomaszewski Farias, Keith Widaman, Rachel Whitmer, Audrey P. Fan, Maria Corrada, Charles DeCarli, Dan Mungas
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
brain signatures of cognition
clinical measurements
cognitive aging
computationally derived biomarkers
Online Access:https://doi.org/10.1002/dad2.70026
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https://doi.org/10.1002/dad2.70026

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