TRIM26 exacerbates pathological cardiac hypertrophy by activating TAK1

TRIM26 exacerbates pathological cardiac hypertrophy by activating TAK1

Pathological myocardial hypertrophy can induce heart failure with high mortality, it is necessary to explore its pathogenesis. Tripartite motif-containing 26 (TRIM26) belongs to the multidomain E3 ubiquitin ligase family. We observed increased expression of TRIM26 in the myocardium of C57BL/6 mice s...

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Bibliographic Details
Main Authors: Xiaochuang Xia, Huajing Shan, Zhaoxia Jin, Tengfei Ma, Yemao Liu, Jianqing Zhang, Han Tian, Bizhen Dong, Chengsheng Xu, Shaoze Chen
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Subjects:
Tripartite motif containing 26
Pathological cardiac hypertrophy
TGF-Beta activated kinase 1
Transverse aortic constriction
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024166844
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