IGF2BP1-mediated methylation of ABCA1 facilitates tumor progression by affecting cholesterol metabolism in lung adenocarcinoma

Abstract ABCA1 is a key protein in maintaining cholesterol homeostasis, and its abnormal expression is associated with the progression of many cancers. Nonetheless, the specific molecular mechanisms by which ABCA1 facilitates the development of LUAD remain largely unexplored, necessitating further i...

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Bibliographic Details
Main Authors: Shaohua Xu, Kai Liu, Zhao Chen, Weijian Tang, Zhoumiao Chen
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Amino Acids
Subjects:
Online Access:https://doi.org/10.1007/s00726-025-03474-1
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