An antibody–drug conjugate for endometrioid carcinoma based on the expression of cell adhesion molecule 1

An antibody–drug conjugate for endometrioid carcinoma based on the expression of cell adhesion molecule 1

Cell adhesion molecule 1 (CADM1), an immunoglobulin superfamily member, is expressed in endometrial glandular cells highly during the proliferative phase but lowly during the secretory phase. Previously, a CADM1–targeting antibody–drug conjugate (ADC) was generated, in which a humanized anti-CADM1 e...

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Bibliographic Details
Main Authors: Man Hagiyama, Azusa Yoneshige, Tomoyuki Otani, Akihiro Wada, Fuka Takeuchi, Yuji Shoya, Takao Inoue, Akihiko Ito
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Molecular & Cellular Oncology
Subjects:
CADM1
early-stage cancer
endometrial hyperplasia
fertility preservation
gynecologic oncology
Online Access:https://www.tandfonline.com/doi/10.1080/23723556.2024.2399379
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https://www.tandfonline.com/doi/10.1080/23723556.2024.2399379

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