Physical model of serum supplemented medium flow in organ-on-a-chip systems.

Physical model of serum supplemented medium flow in organ-on-a-chip systems.

Creating a physiologically relevant shear stress in organ-on-a-chip (OOC) devices requires careful tailoring of microfluidic flow parameters. Currently, it is fairly common to use a simple approximation assuming constant viscosity, even for serum-based media. Here, we show that a popular nutrient so...

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Main Authors: Viesturs Šints, Jānis Cīmurs, Mihails Birjukovs, Ivars Driķis, Karīna Goluba, Kaspars Jēkabsons, Vadims Parfejevs, Una Riekstiņa, Gatis Mozoļevskis, Roberts Rimša, Guntars Kitenbergs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0322069
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https://doi.org/10.1371/journal.pone.0322069

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