Heterocyclic phytometabolites formononetin and arbutin prevent in vitro oxidative and alkylation-induced mutagenicity

Heterocyclic phytometabolites formononetin and arbutin prevent in vitro oxidative and alkylation-induced mutagenicity

Phenolic phytometabolites are promising bioactive compounds for management of genomic instability related diseases. Formononetin (FMN) and arbutin (ARB) are found in several plant sources. Our goal was to investigate the safety and efficacy of FMN and ARB using in vitro both standardized and alterna...

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Bibliographic Details
Main Authors: Lizandra Vitoria de Souza Santos, Barbara Verena Dias Galvão, Lays Souza, Andreia da Silva Fernandes, Carlos Fernando Araujo-Lima, Israel Felzenszwalb
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Toxicology Reports
Subjects:
Phenolic compounds
Toxicogenetic assessment
Antimutagenicity
Chemoprevention
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750024001367
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