PRMT1 alleviates isoprenaline-induced myocardial hypertrophy by methylating SRSF1

PRMT1 alleviates isoprenaline-induced myocardial hypertrophy by methylating SRSF1

Myocardial hypertrophy (MH) is an important factor contributing to severe cardiovascular disease. Previous studies have demonstrated that specific deletion of the protein arginine methyltransferase 1 (PRMT1) leads to MH, but the exact mechanism remains unclear. Serine/arginine-rich splicing factor 1...

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Bibliographic Details
Main Authors: Yan Zi, Zhao Wenhui, Zhao Naixin, Liu Yufeng, Yang Bowen, Wang Li, Liu Jingyi, Wang Deping, Wang Jin, Jiao Xiangying, Cao Jimin, Li Jianguo
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-12-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
myocardial hypertrophy
protein arginine methyltransferase
serine/arginine-rich splicing factor 1
methylation
phosphorylation
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024175
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