Cryoablation of primary breast cancer tumors induces a systemic abscopal effect altering TIME (Tumor Immune Microenvironment) in distant tumors

Cryoablation of primary breast cancer tumors induces a systemic abscopal effect altering TIME (Tumor Immune Microenvironment) in distant tumors

IntroductionDespite recent advances, triple-negative breast cancer (TNBC) patients remain at high risk for recurrence and metastasis, which creates the need for innovative therapeutic approaches to improve patient outcomes. Cryoablation is a promising, less invasive alternative to surgical resection...

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Main Authors: Flávia Sardela de Miranda, Dalia Martinez-Marin, Rachel L. Babcock, Maribel Castro, Geetha P. Boligala, Sonia Y. Khan, Kathryn L. Furr, Isabel Castro-Piedras, Nicholas Wagner, Dakota E. Robison, Karla Daniele, Sharda P. Singh, Kevin Pruitt, Michael W. Melkus, Rakhshanda Layeequr Rahman
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
breast cancer
cryoablation
abscopal effect
RNA-seq analysis
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1498942/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1498942/full

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