Preparation of Bmi-1-siRNA Lipid Nanoparticles and Effects in Gastric Cancer

Malignant tumors remain a serious threat to human health and life and are a major public health problem globally. Herein, we designed and synthesized a novel nucleic acid nanomedicine AS1411-siRNA-LNPs (As@LNPs). Bmi-1 siRNA was coated with cationic liposomes, and a nucleic acid aptamer AS1411 with...

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Bibliographic Details
Main Authors: Hongzhang Yan, Hong Shen, Jinrong SiTu, Yingying Yang, Lingle Zhang, Kai Yang
Format: Article
Language:English
Published: Tsinghua University Press 2024-09-01
Series:Nano Biomedicine and Engineering
Subjects:
Online Access:https://www.sciopen.com/article/10.26599/NBE.2024.9290086
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