Longitudinal changes in KL6 levels predict acute exacerbation in fibrotic interstitial lung disease

Abstract Krebs von den Lungen-6 (KL-6) levels are potentially indicative markers of prospective acute exacerbation (AE) in interstitial lung disease (ILD); however, their longitudinal trends have not been sufficiently investigated. We investigated the predictive ability of patient-specific changes i...

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Bibliographic Details
Main Authors: Akihiro Shiroshita, Keisuke Anan, Chigusa Shirakawa, Hiroshi Shiba, Nobuyuki Yajima
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-12236-8
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