Improved Accessibility of Extracellular Vesicle Surface Molecules Upon Partial Removal of the Protein Corona by High Ionic Strength

Improved Accessibility of Extracellular Vesicle Surface Molecules Upon Partial Removal of the Protein Corona by High Ionic Strength

ABSTRACT Recent studies have confirmed that a biomolecular corona forms around extracellular vesicles (EVs) in biofluids. However, there is limited data on how this adsorbed corona affects the accessibility of EV surface molecules. Here, we investigated various potential corona‐stripping conditions...

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Main Authors: András I. Försönits, Eszter Á. Tóth, Sára Jezsoviczky, Tünde Bárkai, Delaram Khamari, Alicia Galinsoga, Panna Királyhidi, Ágnes Kittel, Júlia Fazakas, Dorina Lenzinger, Hargita Hegyesi, Xabier Osteikoetxea, Tamás Visnovitz, Krisztina Pálóczi, Szilvia Bősze, Edit I. Buzás
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Journal of Extracellular Vesicles
Subjects:
blood plasma
extracellular vesicle
flow cytometry
immunolabelling
protein corona
Online Access:https://doi.org/10.1002/jev2.70124
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https://doi.org/10.1002/jev2.70124

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