Distribution and impact of p16INK4A+ senescent cells in elderly tissues: a focus on senescent immune cell and epithelial dysfunction
Abstract Cellular senescence, recognized as a key hallmark of aging, leads to the accumulation of senescent cells in various tissues over time. While the detrimental effects of these cells on age-related pathological conditions are well-documented, there is still limited information about how senesc...
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| Main Authors: | Soon Sang Park, Young-Kyoung Lee, Young Hwa Kim, So Hyun Park, Hee Young Kang, Jin Cheol Kim, Dong Jun Kim, Su Bin Lim, Gyesoon Yoon, Jang-Hee Kim, Yong Won Choi, Tae Jun Park |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2024-12-01
|
| Series: | Experimental and Molecular Medicine |
| Online Access: | https://doi.org/10.1038/s12276-024-01354-4 |
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