Distribution and impact of p16INK4A+ senescent cells in elderly tissues: a focus on senescent immune cell and epithelial dysfunction

Abstract Cellular senescence, recognized as a key hallmark of aging, leads to the accumulation of senescent cells in various tissues over time. While the detrimental effects of these cells on age-related pathological conditions are well-documented, there is still limited information about how senesc...

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Bibliographic Details
Main Authors: Soon Sang Park, Young-Kyoung Lee, Young Hwa Kim, So Hyun Park, Hee Young Kang, Jin Cheol Kim, Dong Jun Kim, Su Bin Lim, Gyesoon Yoon, Jang-Hee Kim, Yong Won Choi, Tae Jun Park
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01354-4
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