The role of the C5a-C5aR pathway in iron metabolism and gastric cancer progression

The role of the C5a-C5aR pathway in iron metabolism and gastric cancer progression

Gastric cancer continues to be a leading global health concern, with current therapeutic approaches requiring significant improvement. While the disruption of iron metabolism in the advancement of gastric cancer has been well-documented, the underlying regulatory mechanisms remain largely unexplored...

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Bibliographic Details
Main Authors:	Qinxue Ni, Hong Yang, Hang Rao, Liyong Zhang, Mengyuan Xiong, Xiao Han, Boshao Deng, Lulu Wang, Jian Chen, Yan Shi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Immunology
Subjects:	C5a-C5aR pathway gastric cancer iron metabolism macrophage polarization LCN2 ER stress
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1522181/full
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