The role of adipose and muscle tissue breakdown on interorgan energy substrate fluxes in a Pseudomonas aeruginosa induced sepsis model in female pigs

The role of adipose and muscle tissue breakdown on interorgan energy substrate fluxes in a Pseudomonas aeruginosa induced sepsis model in female pigs

Abstract Sepsis leads to an acute breakdown of muscle to support increased caloric and amino acid requirements. Little is known about the role of adipose and muscle tissue breakdown and intestinal metabolism in glucose substrate supply during the acute phase of sepsis. In a translational porcine mod...

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Bibliographic Details
Main Authors: Ryan Morse, Gabriella A. M. Ten Have, John J. Thaden, Marielle P. K. J. Engelen, Sarah Rice, Martin Hagve, Nicolaas E. P. Deutz
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Physiological Reports
Subjects:
amino acid metabolism
gluconeogenesis
glucose
lipid metabolism
pig
sepsis
Online Access:https://doi.org/10.14814/phy2.70129
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https://doi.org/10.14814/phy2.70129

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