Soluble programmed cell death ligand-1 as a predictive biomarker for severity and poor prognosis in pulmonary tuberculosis

Soluble programmed cell death ligand-1 as a predictive biomarker for severity and poor prognosis in pulmonary tuberculosis

Background We aimed to assess whether soluble programmed death-ligand 1 (sPD-L1) could serve as a new biomarker for PTB.Methods Plasma sPD-L1 levels in the discovery cohort were analyzed through flow cytometry and validated by sandwich ELISA. Pleural effusion sPD-L1 levels were measured using ELISA....

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Bibliographic Details
Main Authors: Xiaojue Wang, Weibing Lin, Huimin Li, Sibo Long, Jun Yan, Yiheng Shi, Hongtao Zhang, Xinting Yang, Ling Yi, Guirong Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Annals of Medicine
Subjects:
Pulmonary tuberculosis
sPD-L1
severity
predictive marker
prognosisIntroduction
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2025.2527364
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https://www.tandfonline.com/doi/10.1080/07853890.2025.2527364

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