Comparative proteomic analysis between tumor tissues and intratumoral exosomes from lung adenocarcinoma patients identifies PAFAH1B3 as an exosomal protein key for initiating metastasis in lung adenocarcinoma

Comparative proteomic analysis between tumor tissues and intratumoral exosomes from lung adenocarcinoma patients identifies PAFAH1B3 as an exosomal protein key for initiating metastasis in lung adenocarcinoma

Mounting evidence strongly indicates that exosomes are pivotal in the advancement of cancer, yet the overarching profile of exosomal proteins and their contribution to lung adenocarcinoma (LUAD) progression remain underexplored. In our investigation, we isolated exosomes from treatment-naive LUAD (n...

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Main Authors: Congcong Wang, Ling Xiao, Ling Gao, Jia Wu, Siliang Wang, Miao-Miao Zheng, Chen-Tai Qin, Xian-ge Huang, Lei Zhou, Wei-jie Xu, He-gen Li, Wen-Lian Chen, Li-hua Zhu, Xing Jin
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Heliyon
Subjects:
Proteomics
Exosome
PAFAH1B3
Lung adenocarcinoma
Migration
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024158902
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