Podocyte extracellular vesicles and immune mediators as urinary biomarkers in active lupus nephritis

Abstract Urinary extracellular vesicles (uEVs) and immune mediators have emerged as potential minimally invasive renal biomarkers. Even though active lupus nephritis (LN) is associated with immune complex deposition, tissue inflammation, and podocyte damage, it remains unclear how these parameters a...

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Main Authors: Lilian Alves, Ana Patrícia Lemos, Jessyca Martins, Suellen da Costa Fonseca, Rodrigo Cutrim Gaudio, Higor Lima, Camila Carvalho, Alice Ramos, Gilmar de Souza Lacerda, Pedro Barbosa da Fonseca, Fernanda G. De Felice, Mauro Jorge Cabral-Castro, Jorge Paulo Strogoff de Matos, Jorge Reis Almeida, Dylan Burger, Thalia Medeiros, Andrea Alice Silva
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-08236-3
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