Comparison and combination of mutation and methylation-based urine tests for bladder cancer detection

Comparison and combination of mutation and methylation-based urine tests for bladder cancer detection

Abstract Background and aims Several non-invasive tests for detecting bladder cancer (BC) are commercially available and are based on detecting small panels of BC-associated mutations and/or methylation changes in urine DNA. However, it is not clear which type of biomarker is best, or if a combinati...

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Bibliographic Details
Main Authors: Naheema S. Gordon, Elspeth K. McGuigan, Michaela Ondasova, Jennifer Knight, Laura A. Baxter, Sascha Ott, Robert K. Hastings, Maurice P. Zeegers, Nicholas D. James, K. K. Cheng, Anshita Goel, Minghao Yu, Roland Arnold, Richard T. Bryan, Douglas G. Ward
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Biomarker Research
Subjects:
Bladder cancer
Urine test
Biomarker
Mutation
Methylation
Online Access:https://doi.org/10.1186/s40364-024-00682-x
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