Baicalein inhibits PRRSV through direct binding, targeting EGFR, and enhancing immune response

Baicalein inhibits PRRSV through direct binding, targeting EGFR, and enhancing immune response

Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) presents significant economic challenges to the global pork industry due to its ability to mutate rapidly. The current commercial vaccines have limited effectiveness, and there are strict restrictions on the use of antiviral chemic...

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Bibliographic Details
Main Authors: Jing Wu, Qi Lu, Jing Hou, Yueqin Qiu, Min Tian, Li Wang, Kaiguo Gao, Xuefen Yang, Zongyong Jiang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Veterinary Research
Subjects:
Piglets
PRRSV
baicalein
EGFR
MD simulation
Online Access:https://doi.org/10.1186/s13567-024-01440-5
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