Enhancing the physiological characteristics of chimeric antigen receptor natural killer cells by synthetic biology

Chimeric antigen receptor natural Killer (CAR-NK) cells therapy represents a next-generation immunotherapeutic approach following CAR-T cells therapy, offering inherent “off-the-shelf” compatibility and mitigated off-tumor toxicity. Despite these advantages, clinical translation remains constrained...

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Bibliographic Details
Main Authors: Shuochao Ji, Cheng Jin, Xinjiang Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1592121/full
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