THE HISTORY OF DEFERIPRONE (L1) AND THE COMPLETE TREATMENT OF IRON OVERLOAD IN THALASSAEMIA

Deferiprone (L1) was originally designed, synthesised and screened in vitro and in vivo in 1981 by Kontoghiorghes G J following his discovery of the novel alpha-ketohydroxypyridine class of iron chelators (1978-1981), which were intended for clinical use. The journey through the years for the treatm...

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Bibliographic Details
Main Authors: George J Kontoghiorghes, Marios Kleanthous, Christina N. Kontoghiorghe
Format: Article
Language:English
Published: PAGEPress Publications 2020-01-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Online Access:http://mjhid.org/index.php/mjhid/article/view/4097
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