Impaired immunoproteasomal function exacerbates renal ischemia-reperfusion injury

Impaired immunoproteasomal function exacerbates renal ischemia-reperfusion injury

Oxidative stress caused by reactive oxygen species (ROS) is involved in the pathogenesis of renal ischemia-reperfusion injury (I/R injury), a major cause of acute kidney injury and delayed graft function (DGF). DGF is an early transplant complication that worsens graft prognosis and patient survival...

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Main Authors: Yasushi Ishii, Aya Fukui-Miyazaki, Sari Iwasaki, Takahiro Tsuji, Kiyohiko Hotta, Hajime Sasaki, Shimpei Nakagawa, Takuma Yoshida, Eri Murata, Koji Taniguchi, Nobuo Shinohara, Akihiro Ishizu, Masanori Kasahara, Utano Tomaru
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Experimental and Molecular Pathology
Subjects:
Immunoproteasome
Acute kidney injury
Delayed graft function
Ischemia-reperfusion injury
Oxidative stress
ROS
Online Access:http://www.sciencedirect.com/science/article/pii/S0014480024000583
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