The Impact of Intermediate Antidrug Antibodies to Infliximab and Adalimumab on Clinical Outcomes in Patients with Crohn’s Disease or Ulcerative Colitis
Background: The anti-TNF drugs adalimumab (ADA) and infliximab (IFX) are effective treatments for inflammatory bowel disease (IBD). However, 40% of patients lose response, often due to the development of antibodies-to-ADA (ATA) and antibodies-to-IFX (ATI). While low ATA/ATI titres (<200 ng/mL) a...
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Main Authors: | Chaoyang Wang, Mazen Tolaymat, Raymond Cross |
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Format: | Article |
Language: | English |
Published: |
European Medical Journal
2022-03-01
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Series: | European Medical Journal |
Online Access: | https://www.emjreviews.com/gastroenterology/article/the-impact-of-intermediate-antidrug-antibodies-to-infliximab-and-adalimumab-on-clinical-outcomes-in-patients-with-crohns-disease-or-ulcerative-colitis-j190121/ |
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