Offspring metabolic programming via the maternal diet increases susceptibility to metabolic dysregulationResearch in context

Offspring metabolic programming via the maternal diet increases susceptibility to metabolic dysregulationResearch in context

Summary: Background: Maternal nutrition during critical developmental windows is crucial for offspring metabolic programming. Methionine, an essential amino acid, is crucial in pancreatic differentiation. However, the impact of a maternal methionine-deficiency (MD) diet on offspring during the crit...

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Main Authors: Xuguang Li, Nobuaki Shiraki, Takami Watanabe, Rikako Fukui, Kyohei Furukawa, Yusuke Kato, Yuri Nakahara, Shoen Kume, Akashi Taguchi, Youichiro Wada, Dwina Juliana Warman, Kenji Saito, Haruyo Nakajima-Adachi, Satoshi Hachimura, Hisanori Kato, Huijuan Jia
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:EBioMedicine
Subjects:
Metabolic reprogramming
Maternal nutrient
Offspring health
Pancreatic differentiation
Gut microbiota
Sex differences
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425002610
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