Advanced hybrid computational analysis of febuxostat solubility using machine learning in supercritical processing method
Abstract Over the last decades, industrial employment of supercritical fluids (SCFs) as a trustworthy alternative of organic solvents has increased substantially. SCFs (mainly CO2SCF) have illustrated great potential to improve the solubility of poorly water-soluble drugs. Compared to traditional pr...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-10221-9 |
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