Application of Monoclonal Anti-Mycolate Antibodies in Serological Diagnosis of Tuberculosis

Application of Monoclonal Anti-Mycolate Antibodies in Serological Diagnosis of Tuberculosis

Patient loss to follow-up caused by centralised and expensive diagnostics that are reliant on sputum is a major obstacle in the fight to end tuberculosis. An affordable, non-sputum biomarker-based, point-of-care deployable test is needed to address this. Serum antibodies binding the mycobacterial ce...

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Bibliographic Details
Main Authors: Alma Truyts, Ilse Du Preez, Eldas M. Maesela, Manfred R. Scriba, Les Baillie, Arwyn T. Jones, Kevin J. Land, Jan A. Verschoor, Yolandy Lemmer
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Tropical Medicine and Infectious Disease
Subjects:
tuberculosis
non-sputum-based diagnosis
point-of-care
lateral flow immunoassay
biomarker
mycolic acid
Online Access:https://www.mdpi.com/2414-6366/9/11/269
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