PLK3 weakens antioxidant defense and inhibits proliferation of porcine Leydig cells under oxidative stress

PLK3 weakens antioxidant defense and inhibits proliferation of porcine Leydig cells under oxidative stress

Abstract Aging is characterized by cellular degeneration and impaired physiological functions, leading to a decline in male sexual desire and reproductive capacity. Oxidative stress (OS) lead to testicular aging by impairing the male reproductive system, but the potential mechanisms remain unclear....

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Bibliographic Details
Main Authors: Chujie Chen, Jinyan He, Weixian Huang, Dong Xu, Zhaohui Li, Anqi Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Oxidative stress
Leydig cells
Transcriptome sequencing
PLK3
Online Access:https://doi.org/10.1038/s41598-025-86867-2
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