Clinical Clostridium difficile: clonality and pathogenicity locus diversity.

Clinical Clostridium difficile: clonality and pathogenicity locus diversity.

Clostridium difficile infection (CDI) is an important cause of mortality and morbidity in healthcare settings. The major virulence determinants are large clostridial toxins, toxin A (tcdA) and toxin B (tcdB), encoded within the pathogenicity locus (PaLoc). Isolates vary in pathogenicity from hypervi...

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Main Authors: Kate E Dingle, David Griffiths, Xavier Didelot, Jessica Evans, Alison Vaughan, Melina Kachrimanidou, Nicole Stoesser, Keith A Jolley, Tanya Golubchik, Rosalind M Harding, Tim E Peto, Warren Fawley, A Sarah Walker, Mark Wilcox, Derrick W Crook
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0019993&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0019993&type=printable

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